Disable CD Auto Run

Start regedit and navigate to: 

HKEY_LOCAL_MACHINE\SYSTEM\CurrentControlSet 

\Services\Cdrom. 

Now Create a new registry key of type Dword and name it AutoRun. If the 

key is already there, just set the value to 0 in order to disable AutoRun. To enable it, change 

the value to 1. Once it is done, Exit Registry and Reboot.

NOTE :- Take the backup of your registry (by one of these Software's) before doing any tweak.